A State-of-the-art Approach to Mood Enhancement | Home | About IME-12 | FAQs | Reviews | Clinical Data | Q: What is the daily dosage? A: It is recommended that you take (1.0-1.5 grams) three times daily but it varies from person to person. The benefits last 4-6 hours but some people gravitate to 1 gram twice daily. Virtually anyone who responds favorably to IME-12 need not take more than 1.5 grams at any given time. Generally we recommend not taking IME-12 later than six hours before bedtime so as not to interfere with sleep patterns. Q: Is IME-12 Safe? A:  In a study performed by Springborrn Laboratories, Inc. Spencerville, Ohio, it was determined that an acute dosage of IME-12, nearly 100 times higher than the reported effective dose, can legitimately be considered safer than calcium carbonate, 67% safer than table salt, 92% safer than potassium chloride, and over 1000% times safer than chromium picolinate. Q: Will IME-12 adversely affect athletic drug screening? A: It is a common practice in competitive sports (i.e. Olympics) to screen supplements against the Medpro B SANA test. The possibility that some nutritional supplement could inadvertently interfere with this test is a prevalent concern among competitive athletes, their trainers, and officials. Passing this test demonstrates a certain level of distinction and further supports a claim that IME-12 does not exhibit drug-like activity. Athletic drug screening (Medpro B SANA) following 2 weeks administration at 60mg/kg daily demonstrates that IME-12 will not adversely affect drug testing for 36 classes of regulated substances. We did not screen for steroids but saw no necessity for this. Q: What are the benefits of IME-12? A:  We have data on a prospective open label study that focused on five areas of interest. IME-12 does well with mood support, energy, and motivation. These areas show strong statistical significance with a relatively small sample size.  Reduction in aggression was one area that produced marginal results but may prove statistically significant with a larger sample size. It is possible that certain cravings driven by anxiety may also be diminished with IME-12. Q: How does IME-12 act faster than the competition? A: Many of the supplements being sold for mood support need to be taken for up to two weeks before benefits are evident (i.e St. John’s Wort). Faster acting products like 5-HTP can produce benefits in a week, but IME-12 still takes the lead with benefits being reported (by consumers) as early as 15 minutes to within a few days. Q: What pathways does IME-12 target? A: IME-12 targets norepinephrine (noradrenaline) production and availability. This neurotransmitter helps to regulate mood and emotion.  Scientists believe increased blood flow in a given part of the brain is indicative of increased brain activity. SPECT brain scans following supplementation with IME-12 demonstrate increased activity in the area of the brain responsible for the production of 70% of brain norepinephrine. This fact supports the reported benefits associated with IME-12 supplementation. Q: Is IME-12 a cocoa and almond extract? A: No, IME-12 is a cocoa and almond based formulation but this description is somewhat simplistic. Both the cocoa and almond components provide actives essential to the effectiveness of the product. However, without the supporting formulation, the metabolism of these actives would be far too rapid for any extended benefits. Q: What are the reported side effects associated with IME-12? A: There have been a few reported side effects relatively mild in nature.  Seventy percent of people who supplement with IME-12 report positive benefits with mood, energy, and /or motivation. IME-12 is not recommended for people with  food allergies relating to IME-12 ingredients.